It depends on the heat exchanger...
https://en.wikipedia.org/wiki/Countercurrent_exchange is how things like robins send blood to their legs but don't get frozen solid by the returning chilled fluid.
However I guess most MVHRs will just be one heat exchange matrix and you would be lucky to recover 50%.
I have been mulling over MVHR and probably wouldn't bother with a comprehensive whole-house set-up. I might have a flow and return in our main lounge coming out of the 2 sides of the top of the chimney breast plus another pair in the main bedroom, i.e. the 2 rooms where we spend most time and exhale most moisture...
Then maybe one extract in the bathroom and a supply to the bedroom next to it, possibly another pair split between the 2 front bedrooms.
Not bothering with the kitchen as a) it would foul up the filters and heat exchanger b) it would be difficult to run the duct to it!
A